header photo

Blog posts

Kim To successfully defends her PhD!

Title: Predictive modeling for developmental toxicity of engineered nanomaterials.
 
Abstract: Nanomaterials are defined as particles with at least one dimension on the nanoscale (1-100nm). Although their toxicity is not yet fully understood, nanomaterials present themselves in a wide varie…

Read more

Marissa presents at UNC Environmental Epidemiology Seminar Series

Kosnik M.B., Reif D.M., Lobdell D.T., Astell-Burt T., Feng X., Hader J.D., Hoppin J.A. Associations between access to healthcare, environmental quality, and end-stage renal disease survival time: proportional-hazards models of over 1,000,000 people over 14 years. (manuscript submitted/in revision)

Read more

Marissa presents at U.S. EPA ToxCast Meeting

The seminar was in relation to the forthcoming paper by Kosnik et al. "Concentration-Response Evaluation of ToxCast Compounds for Multivariate Fingerprints of Neural Network Function"

Dylan Wallis joins the Reif Lab!

Bio

Dylan is pursuing his PhD in the Toxicology graduate program.

Reif teaches short course with Ken Rice (University of Washington) at NYU Abu Dhabi's Winter Institute of Statistical Genetics

More information, including registration details and the list of fellow instructors can be found here:

https://nyuadi.secure.force.com/Events/NYUEventRegistration?event=U9fzrcAHenY2P0df1GzIyQ_3D_3D 

Reif gives invited seminar at Paris symposium

The workshop, "Fish and amphibian embryos as alternative models in toxicology and teratology" was organized by the Helmholtz Centre for Environmental Research and hosted at L'Oréal headquarters in Paris, France. 

Read more

Neonatal mice exposed to a high-fat diet in utero influence the behaviour of their nursing dam (2018) Proc R Sci B

Neonatal mice exposed to a high-fat diet in utero influence the behaviour of their nursing dam.

Baptissart M, Lamb HE, To K, Bradish C, Tehrani J, Reif D, Cowley M.

Proc Biol Sci. 2018 Nov 14;285(1891). pii: 20181237. doi: 10.1098/rspb.2018.1237.

PMID: 30429298

Read more

Reif gives seminar at East Carolina University

David Reif gave an invited seminar to East Carolina University's Department of Biology.

GxE publication named an NIEHS "Paper of the Month"

Michele's paper "Elucidating gene-by-environment interactions associated with differential susceptibility to chemical exposure" was cited in the NIEHS newsletter as a Paper of the Month!

https://factor.niehs.nih.gov/2018/9/papers/dert/index.htm

Read more

Marissa presents at ISES-ISEE Meeting in Ottawa

Kosnik M.B., Reif D.M., Lobdell D.T., Astell-Burt T., Feng X., Hader J.D., Hoppin J.A. The
associations between access to care, environmental quality, and end-stage renal disease survival
time. ISES-ISEE Joint Annual Meeting, Ottawa, Canada. Poster.

Updated ToxPi version (v 2.1) available at www.toxpi.org

A major update to the ToxPi interface (version 2.1) is now available at:

www.toxpi.org

This update includes major speed improvements (especially noticeable when clustering large datasets), the ability to zoom/pan on cluster dendrograms, as well as other refinements for GUI users. 

Read more

Marissa's ASHG submission awarded "Reviewer's Choice"

Marissa Kosnik's submission to the 2018 American Society of Human Genetics (ASHG) meeting in San Diego has been selected as a  Reviewers’ Choice Abstract. It means that the abstract scored in the top 10% of poster abstracts as determined by the reviewers’ score.

Read more

Bm-iAANAT and its potential role in fatty acid amide biosynthesis in Bombyx mori

Anderson RL, Battistini MR, Wallis DJ, Shoji C, O'Flynn BG, Dillashaw JE,
Merkler DJ. Bm-iAANAT and its potential role in fatty acid amide biosynthesis in 
Bombyx mori. Prostaglandins Leukot Essent Fatty Acids. 2018 Aug;135:10-17. doi:
10.1016/j.plefa.2018.06.001. Epub 2018 Jun 15. PubMed PMID:…

Read more

Bm-iAANAT and its potential role in fatty acid amide biosynthesis in Bombyx mori

Anderson RL, Battistini MR, Wallis DJ, Shoji C, O'Flynn BG, Dillashaw JE,
Merkler DJ. Bm-iAANAT and its potential role in fatty acid amide biosynthesis in 
Bombyx mori. Prostaglandins Leukot Essent Fatty Acids. 2018 Aug;135:10-17. doi:
10.1016/j.plefa.2018.06.001. Epub 2018 Jun 15. PubMed PMID:…

Read more

Elucidating Gene-by-Environment Interactions Associated with Differential Susceptibility to Chemical Exposure (2018) EHP

Full paper:

https://ehp.niehs.nih.gov/EHP2662/

PubMed:

https://www.ncbi.nlm.nih.gov/pubmed/29968567

News releases and press coverage:

https://news.ncsu.edu/2018/06/reif-genes-environment/

https://www.sciencedaily.com/releases/2018/06/180629114700.htm
 
https://globalhealthnewswire.com/2018/…

Read more

Kim To presents at BioLunch Seminar Series

Kim To presented a seminar entitled "Developmental Toxicity of Engineered Nanomaterials in Zebrafish Embryos" at the BioLunch Seminar Series.

Characterizing the effects of missing data and evaluating imputation methods for chemical prioritization applications using ToxPi (2018) BioData Mining

Kimberly T. To, Rebecca C. Fry, David M. Reif. Characterizing the effects of missing data and evaluating imputation methods for chemical prioritization applications using ToxPi. BioData Mining. 2018. 

https://rdcu.be/XYtJ

 

Reif appointed to National Academy of Sciences (NAS) committee

Scoping Plan to Assess the Hazards of Organohalogen Flame Retardants 

https://www8.nationalacademies.org/cp/CommitteeView.aspx?key=49937

Confirmation of high-throughput screening data and novel mechanistic insights into VDR-xenobiotic interactions by orthogonal assays (2018) Scientific Reports

Mahapatra D, Franzosa JA, Roell K, Kuenemann MA, Houck KA, Reif DM, Fourches
D, Kullman SW. Confirmation of high-throughput screening data and novel
mechanistic insights into VDR-xenobiotic interactions by orthogonal assays. Sci
Rep. 2018 Jun 11;8(1):8883. doi: 10.1038/s41598-018-27055-3. PubMe…

Read more

Kyle Roell successfully defends his PhD!

Kyle Roell successfully defended his PhD, entitled "Statistical Methods for Assessing the Genetic Etiology of Synergistic Drug Interactions".

Dr. Kyle Roell is currently a postdoc with Stephanie Engel in the Department of Epidemiology at UNC Chapel Hill.

Read more

20 blog posts