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Blog posts

Wildfires and extracellular vesicles: Exosomal MicroRNAs as mediators of cross-tissue cardiopulmonary responses to biomass smoke (2022) Environ Int.

Carberry CK, Koval LE, Payton A, Hartwell H, Ho Kim Y, Smith GJ, Reif DM, Jaspers I, Ian Gilmour M, Rager JE. Wildfires and extracellular vesicles: Exosomal MicroRNAs as mediators of cross-tissue cardiopulmonary responses to biomass smoke. Environ Int. 2022 Jul 16;167:107419. doi: 10.1016/j.envint.2…

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New NIH R01 grant awarded! "Characterizing Gene-Environment Interactions that Affect Individual Susceptibility to an Expanding Chemical Exposome"

Environmental chemical exposure has been linked to increases in cancer incidence, birth and developmental defects, impaired cognitive development, and neurodegenerative disease. However, even as the number of manufactured chemicals in the environment grows into the hundreds-of-thousands, comprehensi…

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Development of the InTelligence And Machine LEarning (TAME) Toolkit for Introductory Data Science, Chemical-Biological Analyses, Predictive Modeling, and Database Mining for Environmental Health Research (2022) Front. Tox

Kyle Roell, Lauren E. Koval, Rebecca Boyles, Grace Patlewicz, Caroline Ring, Cynthia V. Rider, Cavin Ward-Caviness, David M. Reif, Ilona Jaspers, Rebecca C. Fry and Julia E. Rager. Development of the InTelligence And Machine LEarning (TAME) Toolkit for Introductory Data Science, Chemical-Biological …

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Preethi selected for A2i program

Preethi Thunga was selected to take part in the Accelerate to Industry (A2i)™program with the NC State Graduate School. This selective program advances professional development skills, with an emphasis on leadership, teamwork, and communication. For more details, see:

https://grad.ncsu.edu/pro…

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New NIH R35 RIVER grant (PI Robyn Tanguay) awarded!

David is part of a new, 8-year R35 RIVER grant from the National Institute of Environmental Health Sciences (R35ES031709) for the project “Discovering Chemical Activity Networks-Predicting Bioactivity Based on Structure.” The project builds on the long-standing collaboration with Robyn Tanguay at Or…

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David participates in the "From Free Radicals to Key Characteristics" workshop at UC Berkeley

The event brought together experts to celebrate the leadership of Prof. Martyn Smith in developing the "Key Characteristics of Human Carcinogens" and collaborate on future directions for the Key Characteristics approach.

https://www.eventbrite.com/e/from-free-radicals-to-key-characteristics-ticke…

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David participates in NAS workshop on Artificial Intelligence and Open Data Practices in Chemical Hazard Assessment

David served on the planning committee and moderated sessions as part of the National Academy of Sciences (NAS) Workshops to Support EPA's Development of Human Health Assessments: Artificial Intelligence and Open Data Practices in Chemical Hazard Assessment

https://www.nationalacademies.org/event…

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Jessie wins 2nd place for her poster at SETAC Nontarget Analysis for Environmental Risk Assessment!

A Novel Approach to Evaluating Disease Risk Through the Incorporation of Machine Learning and Lipidomic Data

Jessie Chappel, Mary King, Rachel DeHoog, Livia S. Eberlin, David Reif, Erin S. Baker

https://twitter.com/BakerlabNCSU/status/1528756028728385538/photo/2

https://twitter.com/bakerlab…

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Data Science educational toolkit presented at the Superfund DMAC Quarterly Meeting

The inTelligence And Machine lEarning (TAME) Toolkit for Introductory Data Science, Chemical-Biological Analyses, Predictive Modeling, and Database Mining for Environmental Health Research

Kyle R. Roell, Lauren E. Koval, Rebecca Boyles, Grace Patlewicz, Caroline Ring, Cynthia Rider, Cavin Ward-Ca…

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David participates in NAS workshop on Triangulation of Evidence in Environmental Epidemiology

David served on the planning committee as part of the National Academy of Sciences (NAS) Workshops to Support EPA's Development of Human Health Assessments: Triangulation of Evidence in Environmental Epidemiology

https://www.nationalacademies.org/event/05-09-2022/workshops-to-support-epas-deve…

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Nnamdi's work on using Bioinformatics to improve health equity featured in Superfund newsletter

https://tools.niehs.nih.gov/srp/1/eposted/pdfs/srp_e_posted_notes_2022_05_06_508.pdf

Comparison of National Vulnerability Indices Used by the Centers for Disease Control and Prevention for the COVID-19 Response (2022) Public Health Reports

Wolkin A, Collier S, House J, Reif D, Motsinger-Reif A, Duca L, Sharpe D. Comparison of National Vulnerability Indices Used by the Centers for Disease Control and Prevention for the COVID-19 Response. Public Health Rep. 2022 May 5:333549221090262. doi: 10.1177/00333549221090262. Epub ahead of print.…

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Principles of Toxicology: Environmental and Industrial Applications, 4th Edition

Principles of Toxicology: Environmental and Industrial Applications, 4th Edition. Stephen M. Roberts (Editor), Robert C. James (Editor), Phillip L. Williams (Editor). ISBN: 978-1-119-63516-1.

David Reif co-authored Chapter 6 "Computational Toxicology", with Richard S. Judson, David M. Reif, Keit…

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Leveraging a High-Throughput Screening Method to Identify Mechanisms of Individual Susceptibility Differences in a Genetically Diverse Zebrafish Model (2022) Frontiers in Toxicology

Dylan James Wallis, Jane La Du, Preethi Thunga, Daniel Elson, Lisa Truong, Siva Kumar Kolluri, Robyn Leigh Tanguay, David M Reif. Leveraging a High-Throughput Screening Method to Identify Mechanisms of Individual Susceptibility Differences in a Genetically Diverse Zebrafish Model. 29 April 2022. Fro…

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ToxPi*GIS Toolkit: creating, viewing, and sharing integrative visualizations for geospatial data using ArcGIS (2022) J Expo Sci Environ Epidemiol.

Fleming J, Marvel SW, Supak S, Motsinger-Reif AA, Reif DM. ToxPi*GIS Toolkit: creating, viewing, and sharing integrative visualizations for geospatial data using ArcGIS. J Expo Sci Environ Epidemiol. 2022 Apr 26. doi: 10.1038/s41370-022-00433-w. Epub ahead of print. PMID: 35474345.

doi: 10.1038/s…

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Jonathon passes PhD Qual Exam!

Jonathon passed his Bioinformatics Qualifying Exam and is now a candidate for the PhD in Bioinformatics!

David presents to Bioinformatics Users Group (BUGs) + toxpiR now available on High-Performance Computing Cluster

David presented on software options available for ToxPi to the university-wide Bioinformatics Users Group (BUGs). Thanks to Lisa Lowe for installing and documenting the new toxpiR package on the HPC cluster (Github link).

Links to all versions of ToxPi are available at https://toxpi.org

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Convergent evolution of polyploid genomes from across the eukaryotic tree of life (2022) G3

Hao Y, Fleming J, Petterson J, Lyons E, Edger PP, Pires JC, Thorne JL, Conant GC. Convergent evolution of polyploid genomes from across the eukaryotic tree of life. G3 (Bethesda). 2022 Apr 22:jkac094. doi: 10.1093/g3journal/jkac094. Epub ahead of print. PMID: 35451464.

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David part of Science Advisory Committee on Chemicals (SACC) for "Toxic Substances Control Act (TSCA) Systematic Review Protocol"

https://www.epa.gov/tsca-peer-review/peer-review-draft-tsca-systematic-review-protocol

On April 19-21, 2022, EPA held a public virtual meeting of the Science Advisory Committee on Chemicals (SACC) to peer review the draft Toxic Substances Control Act (TSCA) Systematic Review Protocol. This protoc…

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The Ahr2-Dependent wfikkn1 Gene Influences Zebrafish Transcriptome, Proteome, and Behavior (2022) Toxicological Sciences

Shankar P, Garcia GR, LaDu JK, Sullivan CM, Dunham CL, Goodale BC, Waters KM, Stanisheuski S, Maier CS, Thunga P, Reif DM, Tanguay RL. The Ahr2-Dependent wfikkn1 Gene Influences Zebrafish Transcriptome, Proteome, and Behavior. Toxicol Sci. 2022 Apr 4:kfac037. doi: 10.1093/toxsci/kfac037. Epub ahead …

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20 blog posts