header photo

Blog posts : "Publications"

Integration of curated and high-throughput screening data to elucidate environmental influences on disease pathways (2019) Computational Toxicology

Vaccines and science communication

A recent article by Sarah Zhang in The Atlantic illustrates the importance of science communication with regard to vaccinomics:

https://www.theatlantic.com/science/archive/2019/05/vaccines-dna-23andme/589915/

 

Part of that article details how one of our past papers has been interpreted, …

Read more

Reif co-authors National Academy of Sciences (NAS) report "A Class Approach to Hazard Assessment of Organohalogen Flame Retardants"

Systematic determination of the relationship between nanoparticle core diameter and toxicity for a series of structurally analogous gold nanoparticles in zebrafish (2019) Nanotoxicology

https://www.tandfonline.com/doi/full/10.1080/17435390.2019.1592259

 

Truong, L.; Zaikova, T.; Baldock, B.L.; Balik-Meisner, M.; To, K.; Reif, D.M.; Kennedy, Z.C.; Hutchison, J.E.; Tanguay, R.L. “Systematic determination of the relationship between nanoparticle core diameter and toxicity for a…

Read more

Associations between access to healthcare, environmental quality, and end-stage renal disease survival time: Proportional-hazards models of over 1,000,000 people over 14 years (2019) PLoS One

Kosnik MB, Reif DM, Lobdell DT, Astell-Burt T, Feng X, Hader JD, Hoppin JA.
Associations between access to healthcare, environmental quality, and end-stage
renal disease survival time: Proportional-hazards models of over 1,000,000 people
over 14 years. PLoS One. 2019 Mar 21;14(3):e0214094. doi:…

Read more

Neonatal mice exposed to a high-fat diet in utero influence the behaviour of their nursing dam (2018) Proc R Sci B

Neonatal mice exposed to a high-fat diet in utero influence the behaviour of their nursing dam.

Baptissart M, Lamb HE, To K, Bradish C, Tehrani J, Reif D, Cowley M.

Proc Biol Sci. 2018 Nov 14;285(1891). pii: 20181237. doi: 10.1098/rspb.2018.1237.

PMID: 30429298

Read more

GxE publication named an NIEHS "Paper of the Month"

Michele's paper "Elucidating gene-by-environment interactions associated with differential susceptibility to chemical exposure" was cited in the NIEHS newsletter as a Paper of the Month!

https://factor.niehs.nih.gov/2018/9/papers/dert/index.htm

Read more

Bm-iAANAT and its potential role in fatty acid amide biosynthesis in Bombyx mori

Anderson RL, Battistini MR, Wallis DJ, Shoji C, O'Flynn BG, Dillashaw JE,
Merkler DJ. Bm-iAANAT and its potential role in fatty acid amide biosynthesis in 
Bombyx mori. Prostaglandins Leukot Essent Fatty Acids. 2018 Aug;135:10-17. doi:
10.1016/j.plefa.2018.06.001. Epub 2018 Jun 15. PubMed PMID:…

Read more

Bm-iAANAT and its potential role in fatty acid amide biosynthesis in Bombyx mori

Anderson RL, Battistini MR, Wallis DJ, Shoji C, O'Flynn BG, Dillashaw JE,
Merkler DJ. Bm-iAANAT and its potential role in fatty acid amide biosynthesis in 
Bombyx mori. Prostaglandins Leukot Essent Fatty Acids. 2018 Aug;135:10-17. doi:
10.1016/j.plefa.2018.06.001. Epub 2018 Jun 15. PubMed PMID:…

Read more

Elucidating Gene-by-Environment Interactions Associated with Differential Susceptibility to Chemical Exposure (2018) EHP

Full paper:

https://ehp.niehs.nih.gov/EHP2662/

PubMed:

https://www.ncbi.nlm.nih.gov/pubmed/29968567

News releases and press coverage:

https://news.ncsu.edu/2018/06/reif-genes-environment/

https://www.sciencedaily.com/releases/2018/06/180629114700.htm
 
https://globalhealthnewswire.com/2018/…

Read more

Characterizing the effects of missing data and evaluating imputation methods for chemical prioritization applications using ToxPi (2018) BioData Mining

Kimberly T. To, Rebecca C. Fry, David M. Reif. Characterizing the effects of missing data and evaluating imputation methods for chemical prioritization applications using ToxPi. BioData Mining. 2018. 

https://rdcu.be/XYtJ

 

Confirmation of high-throughput screening data and novel mechanistic insights into VDR-xenobiotic interactions by orthogonal assays (2018) Scientific Reports

Mahapatra D, Franzosa JA, Roell K, Kuenemann MA, Houck KA, Reif DM, Fourches
D, Kullman SW. Confirmation of high-throughput screening data and novel
mechanistic insights into VDR-xenobiotic interactions by orthogonal assays. Sci
Rep. 2018 Jun 11;8(1):8883. doi: 10.1038/s41598-018-27055-3. PubMe…

Read more

ToxPi Graphical User Interface 2.0: Dynamic exploration, visualization, and sharing of integrated data models (2018) BMC Bioinformatics

Marvel SW, To K, Grimm FA, Wright FA, Rusyn I, Reif DM. ToxPi Graphical User Interface 2.0: Dynamic exploration, visualization, and sharing of integrated data models. BMC Bioinformatics. 2018 Mar 5;19(1):80. doi: 10.1186/s12859-018-2089-2. PubMed PMID: 29506467.

 

https://bmcbioinformatics.bi…

Read more

Population genetic diversity in zebrafish lines (2018) Mammalian Genome

Balik-Meisner M, Truong L, Scholl EH, Tanguay RL, Reif DM. Population genetic 
diversity in zebrafish lines. Mamm Genome. 2018 Jan 24. doi:
10.1007/s00335-018-9735-x. [Epub ahead of print] PubMed PMID: 29368091.

https://www.ncbi.nlm.nih.gov/pubmed/29368091

 

 

 

Read more

Use of high-throughput in vitro toxicity screening data in cancer hazard evaluations by IARC Monograph Working Groups (2017) ALTEX

Transgenerational inheritance of neurobehavioral and physiological deficits from developmental exposure to benzo [a] pyrene in zebrafish (2017) Toxicology and Applied Pharmacology

Knecht AL, Truong L, Marvel SW, Reif DM, Garcia A, Lu C, Simonich MT,
Teeguarden JG, Tanguay RL. Transgenerational inheritance of neurobehavioral and
physiological deficits from developmental exposure to benzo[a]pyrene in
zebrafish. Toxicol Appl Pharmacol. 2017 Jun 3;329:148-157. doi:
10.1016/…

Read more

An introduction to terminology and methodology of chemical synergy -perspectives from across disciplines (2017) Frontiers in Pharmacology

Integrating Morphological and Behavioral Phenotypes in Developing Zebrafish

Zhang G., Truong L., Tanguay R.L., Reif D.M. (2017) Integrating Morphological and Behavioral Phenotypes in Developing Zebrafish. In: Kalueff A. (eds) The rights and wrongs of zebrafish: Behavioral phenotyping of zebrafish. Springer, Cham.

http://www.springer.com/us/book/9783319337739

https://l…

Read more

Incorporating ToxCast and Tox21 datasets to rank biological activity of chemicals at Superfund sites in North Carolina (2017) Environment International

Read more

A New Statistical Approach to Characterize Chemical-Elicited Behavioral Effects in High-Throughput Studies Using Zebrafish (2017) PLoS One

Read more

20 blog posts