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Blog posts

Center for Human Health and the Environment (CHHE) Receives $7.6M Funding Renewal

 

David is co-Director of the Integrated Health Science Facility Core for the NIEHS P30-funded Center for Human Health and the Environment (CHHE). The press release announcing the grant renewal is here:

https://sciences.ncsu.edu/news/center-for-human-health-and-the-environment-receives-7-6…

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In vivo assessment of respiratory burst inhibition by xenobiotic exposure using larval zebrafish (2020) Immunotoxicology

Drake W. Phelps, Ashley A. Fletcher, Ivan Rodriguez-Nunez, Michele R. Balik-Meisner, Debra A. Tokarz, David M. Reif, Dori R. Germolec & Jeffrey A. Yoder (2020) In vivo assessment of respiratory burst inhibition by xenobiotic exposure using larval zebrafish, Journal of Immunotoxicology, 17:1, 94-104,…

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New P42 (Superfund Research Program) award: Center for Environmental and Human Health Effects of PFAS

See the full news release "NC State Receives $7.4 Million from NIEHS to Study PFAS Toxicity, Bioaccumulation and Remediation" @ https://news.ncsu.edu/2020/03/niehs-pfas-center/

David Reif and Denis Fourches will lead the Data Management and Analysis Core (DMAC) for the new center. More informat…

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Adrian chairs session at the symposium "Interactions Between the Brain and the Environment"

Adrian Green chaired the opening session of the Fourth Annual CHHE Symposium

This year's theme was the exploration of the importance of environmental exposures on the brain, behavior, and neurodevelopmental outcomes. 

 

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Paper on social behavior effects of flame retardants (Gillera et al.) recognized as NIEHS Extramural Paper of the Month

https://factor.niehs.nih.gov/2020/1/papers/dert/index.htm

 

Gillera SEA, Marinello WP, Horman BM, Phillips AL, Ruis MT, Stapleton HM, Reif DM, Patisaul HB. 2019. Sex-specific effects of perinatal FireMaster 550 (FM 550) exposure on socioemotional behavior in prairie voles. Neurotoxicol Tera…

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Establishment of a new FDA-sponsored Botanical Safety Consortium

David is a Data Analysis working group member in the new U.S. Food and Drug Administration (FDA) Botanical Safety Consortium, a public-private partnership of industry, academia, and government that will promote scientific advances in evaluating the safety of botanical ingredients and mixtures in die…

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HGBEnviroScreen: Enabling Community Action through Data Integration in the Houston–Galveston– Brazoria Region (2020) International Journal of Environmental Research and Public Health

Sharmila Bhandari, P. Grace Tee Lewis, Elena Craft, Skylar W. Marvel, David M. Reif, and Weihsueh A. Chiu. HGBEnviroScreen: Enabling Community Action through Data Integration in the Houston–Galveston–Brazoria Region. Int. J. …

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David talks with aspiring scientists at the Computational Biology Club meeting

David talked to a group of undergrads interested in exploring careers in science as part of the Computational Biology Club

Thanks for club president Pooja Parameswaran for organizing the event!

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David joins the Editorial Board of Frontiers in Toxicology

David Reif has joined the Editorial Board of the Neurotoxicology specialty section of Frontiers in Toxicology.

https://www.frontiersin.org/journals/toxicology#editorial-board

Concentration-response evaluation of ToxCast compounds for multivariate activity patterns of neural network function (2019) Arch Toxicol

Kosnik MB, Strickland JD, Marvel SW, Wallis DJ, Wallace K, Richard AM, Reif
DM, Shafer TJ. Concentration-response evaluation of ToxCast compounds for
multivariate activity patterns of neural network function. Arch Toxicol. 2019 Dec
10. doi: 10.1007/s00204-019-02636-x. [Epub ahead of print] PubM…

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Sex-specific effects of perinatal FireMaster® 550 (FM 550) exposure on socioemotional behavior in prairie voles (2019) Neurotoxicology and Teratology

Gillera SEA, Marinello WP, Horman BM, Phillips AL, Ruis MT, Stapleton HM, Reif
DM, Patisaul HB. Sex-specific effects of perinatal FireMaster® 550 (FM 550)
exposure on socioemotional behavior in prairie voles. Neurotoxicol Teratol. 2019 
Nov 12:106840. doi: 10.1016/j.ntt.2019.106840. [Epub ahead…

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Multivariate modeling of engineered nanomaterial features associated with developmental toxicity (2019) NanoImpact

 

KT To, L Truong, S Edwards, RL Tanguay, DM Reif (2019) Multivariate modeling of engineered nanomaterial features associated with developmental toxicity, NanoImpact.

 

 

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Marissa wins award for presentation at International Neurotoxicology Association meeting in Germany

Marissa Kosnik won an INA student poster award for her poster presentation at the International Neurotoxicology Association meeting in Dusseldorf, Germany.

Melody Hancock joins the Reif Lab!

Melody Hancock is a Master of Physiology student at NC State University. She received her B.S. in Biochemistry and Molecular Biology, with a double major in Spanish, from Mercer University in Macon, GA. Her research focuses on methods for optimizing multivariate profiling methods, such as ToxPi, for…

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David presents at INA meeting in Germany

David presented a platform presentation at the at the International Neurotoxicology Association meeting in Dusseldorf, Germany. 

David's talked was entitled "The power of data integration for systems neurotoxicology".  It was given as part of the  session "Systems neurotoxicology: From in v…

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Synergistic chemotherapy drug response is a genetic trait in lymphoblastoid cell lines (2019) Frontiers in Genetics

Kyle Roell, Tammy Havener, David Reif*, John Jack, Howard McLeod, Tim Wiltshire, Alison Motsinger-Reif*

Front. Genet. | doi: 10.3389/fgene.2019.00829

Synergistic chemotherapy drug response is a genetic trait in lymphoblastoid cell lines

Lymphoblastoid cell lines (LCL) are a high…

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Population-based toxicity screening in human induced pluripotent stem cell-derived cardiomyocytes (2019) Toxicol Appl Pharmacol

Burnett SD, Blanchette AD, Grimm FA, House JS, Reif DM, Wright FA, Chiu WA,
Rusyn I. Population-based toxicity screening in human induced pluripotent stem
cell-derived cardiomyocytes. Toxicol Appl Pharmacol. 2019 Aug 16;381:114711. doi:
10.1016/j.taap.2019.114711. [Epub ahead of print] PubMed P…

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Knockdown of arylalkylamine N-acetyltransferase-like 2 in Drosophila melanogaster (2019) Arch Insect Biochem Physiol

Anderson RL, Wallis DJ, Aguirre A, Holliday D, Merkler DJ. Knockdown of
arylalkylamine N-acetyltransferase-like 2 in Drosophila melanogaster. Arch Insect
Biochem Physiol. 2019 Aug 6:e21608. doi: 10.1002/arch.21608. [Epub ahead of
print] PubMed PMID: 31385627.

 

https://www.ncbi.nlm.nih.g…

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David's interview with local ESPN Radio Station

Dave Thomas of ESPN Radio Harrisonburg interviewed David to talk about how lessons learned in sports (High School athletics, in this case) relate to one's career.

A recording of their conversation can be found here:

https://espnharrisonburg.com/podcasts/daily-sports-feed-07-19-19-david-reif/ …

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Determination of chemical-disease risk values to prioritize connections between environmental factors, genetic variants, and human diseases (2019) Toxicology and Applied Pharmacology

Kosnik MB, Reif DM. Determination of chemical-disease risk values to
prioritize connections between environmental factors, genetic variants, and human
diseases. Toxicol Appl Pharmacol. 2019 Jul 16:114674. doi:
10.1016/j.taap.2019.114674. [Epub ahead of print] PubMed PMID: 31323264.
20 blog posts