Kirkwood-Donelson KI, Chappel J, Tobin E, Dodds JN, Reif DM, DeWitt JC, Baker ES. Investigating mouse hepatic lipidome dysregulation following exposure to emerging per- and polyfluoroalkyl substances (PFAS). Chemosphere. 2024 Mar 8:141654. doi: 10.1016/j.chemosphere.2024.141654. Epub ahead of print.…
Blog posts
Guided optimization of ToxPi model weights using a Semi-Automated approach (2024) Computational Toxicology
Jonathon F Fleming, John S House, Jessie R Chappel, Alison A Motsinger-Reif, David M Reif. Guided optimization of ToxPi model weights using a Semi-Automated approach. Computational Toxicology. 2024/3/1.
Uncovering the common factors of chemical exposure and behavior: Evaluating behavioral effects across a testing battery using factor analysis (2023) Neurotoxicology
Marinello WP, Gillera SEA, Huang L, Rollman J, Reif DM, Patisaul HB. Uncovering the common factors of chemical exposure and behavior: Evaluating behavioral effects across a testing battery using factor analysis. Neurotoxicology. 2023 Dec;99:264-273. doi: 10.1016/j.neuro.2023.10.012. Epub 2023 Oct 31…
The relationship between greenspace exposure and telomere length in the National Health and Nutrition Examination Survey (2023) Sci Total Environ
Ogletree SS, Huang JH, Reif D, Yang L, Dunstan C, Osakwe N, Oh JI, Hipp JA. The relationship between greenspace exposure and telomere length in the National Health and Nutrition Examination Survey. Sci Total Environ. 2023 Dec 20;905:167452. doi: 10.1016/j.scitotenv.2023.167452. Epub 2023 Sep 28. PMI…
From big data to big insights: statistical and bioinformatic approaches for exploring the lipidome (2023) Anal Bioanal Chem
Chappel JR, Kirkwood-Donelson KI, Reif DM, Baker ES. From big data to big insights: statistical and bioinformatic approaches for exploring the lipidome. Anal Bioanal Chem. 2023 Oct 25. doi: 10.1007/s00216-023-04991-2. Epub ahead of print. PMID: 37875675.
Estimation of the Half-Lives of Recently Detected Per- and Polyfluorinated Alkyl Ethers in an Exposed Community (2023) Environ Sci Technol
Wallis DJ, Kotlarz N, Knappe DRU, Collier DN, Lea CS, Reif D, McCord J, Strynar M, DeWitt JC, Hoppin JA. Estimation of the Half-Lives of Recently Detected Per- and Polyfluorinated Alkyl Ethers in an Exposed Community. Environ Sci Technol. 2023 Oct 17;57(41):15348-15355. doi: 10.1021/acs.est.2c08241.…
Aggregated Molecular Phenotype Scores: Enhancing Assessment and Visualization of Mass Spectrometry Imaging Data for Tissue-Based Diagnostics (2023) Anal Chem
Chappel JR, King ME, Fleming J, Eberlin LS, Reif DM, Baker ES. Aggregated Molecular Phenotype Scores: Enhancing Assessment and Visualization of Mass Spectrometry Imaging Data for Tissue-Based Diagnostics. Anal Chem. 2023 Aug 29;95(34):12913-12922. doi: 10.1021/acs.analchem.3c02389. Epub 2023 Aug 14.…
Pharmacogenomic Analyses Implicate B Cell Developmental Status and MKL1 as Determinants of Sensitivity toward Anti-CD20 Monoclonal Antibody Therapy (2023) Cells
Small GW, Akhtari FS, Green AJ, Havener TM, Sikes M, Quintanhila J, Gonzalez RD, Reif DM, Motsinger-Reif AA, McLeod HL, Wiltshire T. Pharmacogenomic Analyses Implicate B Cell Developmental Status and MKL1 as Determinants of Sensitivity toward Anti-CD20 Monoclonal Antibody Therapy. Cells. 2023 Jun 7…
MKX-AS1 Gene Expression Associated with Variation in Drug Response to Oxaliplatin and Clinical Outcomes in Colorectal Cancer Patients (2023) Pharmaceuticals
Gonzalez RD, Small GW, Green AJ, Akhtari FS, Motsinger-Reif AA, Quintanilha JCF, Havener TM, Reif DM, McLeod HL, Wiltshire T. MKX-AS1 Gene Expression Associated with Variation in Drug Response to Oxaliplatin and Clinical Outcomes in Colorectal Cancer Patients. Pharmaceuticals (Basel). 2023 May 17;1…
RYK Gene Expression Associated with Drug Response Variation of Temozolomide and Clinical Outcomes in Glioma Patients (2023) Pharmaceuticals
Gonzalez RD, Small GW, Green AJ, Akhtari FS, Havener TM, Quintanilha JCF, Cipriani AB, Reif DM, McLeod HL, Motsinger-Reif AA, Wiltshire T. RYK Gene Expression Associated with Drug Response Variation of Temozolomide and Clinical Outcomes in Glioma Patients. Pharmaceuticals. 2023; 16(5):726. https:…
Legacy and emerging per- and polyfluoroalkyl substances suppress the neutrophil respiratory burst (2023) J Immunotoxicol
Phelps DW, Palekar AI, Conley HE, Ferrero G, Driggers JH, Linder KE, Kullman SW, Reif DM, Sheats MK, DeWitt JC, Yoder JA. Legacy and emerging per- and polyfluoroalkyl substances suppress the neutrophil respiratory burst. J Immunotoxicol. 2023 Dec;20(1):2176953. doi: 10.1080/1547691X.2023.2176953. PM…
Bayesian matrix completion for hypothesis testing (2023) J R Stat Soc Ser C Appl Stat.
Jin B, Dunson DB, Rager JE, Reif DM, Engel SM, Herring AH. Bayesian matrix completion for hypothesis testing. J R Stat Soc Ser C Appl Stat. 2023 Mar 15;72(2):254-270. doi: 10.1093/jrsssc/qlac005. PMID: 37197290; PMCID: PMC10184491.
Utilizing a Population-Genetic Framework to Test for Gene-Environment Interactions between Zebrafish Behavior and Chemical Exposure (2022) Toxics
Thunga P, Truong L, Rericha Y, Du J, Morshead M, Tanguay RL, Reif DM. Utilizing a Population-Genetic Framework to Test for Gene-Environment Interactions between Zebrafish Behavior and Chemical Exposure. Toxics. 2022 Dec 9;10(12):769. doi: 10.3390/toxics10120769. PMID: 36548602; PMCID: PMC9781692.
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Preethi successfully defends her PhD dissertation!!!
Preethi Thunga successfully defended her PhD dissertation, entitled 'Using zebrafish behavior to study gene-environment interactions after chemical exposures".
David joins NIEHS as Chief of the Predictive Toxicology Branch (PTB) in the Division of Translational Toxicology (DTT)
David joined NIH/NIEHS/DTT as Chief of the Predictive Toxicology Branch in October 2022.
The Predictive Toxicology Branch (PTB) partners across the NIEHS Division of Translational Toxicology (DTT) to develop and apply innovative approaches to predict human-relevant health effects from agents of …
Dylan joins U.S. EPA as a postdoc in the Center for Public Health and Environmental Assessment
Dr. Dylan Wallis is now a postdoc at the U.S. EPA Center for Public Health and Environmental Assessment with Dr. Jeffrey Minucci.
Retreat and student exchange with Tanguay Lab
Following a joint scientific retreat with Robyn Tanguay's group at Oregon State University (Including a beautiful waterfall hike!), they generously hosted Preethi Thunga at SARL so that she could gain better understanding of data generation for her dissertation work.
Adrian joins Sciome as a Senior Computational Toxicologist
Dr. Adrian Green has joined Sciome as a Senior Computational Toxicologist.
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