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RYK Gene Expression Associated with Drug Response Variation of Temozolomide and Clinical Outcomes in Glioma Patients (2023) Pharmaceuticals

Gonzalez RD, Small GW, Green AJ, Akhtari FS, Havener TM, Quintanilha JCF, Cipriani AB, Reif DM, McLeod HL, Motsinger-Reif AA, Wiltshire T. RYK Gene Expression Associated with Drug Response Variation of Temozolomide and Clinical Outcomes in Glioma Patients. Pharmaceuticals. 2023; 16(5):726. https:…

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Legacy and emerging per- and polyfluoroalkyl substances suppress the neutrophil respiratory burst (2023) J Immunotoxicol

Phelps DW, Palekar AI, Conley HE, Ferrero G, Driggers JH, Linder KE, Kullman SW, Reif DM, Sheats MK, DeWitt JC, Yoder JA. Legacy and emerging per- and polyfluoroalkyl substances suppress the neutrophil respiratory burst. J Immunotoxicol. 2023 Dec;20(1):2176953. doi: 10.1080/1547691X.2023.2176953. PM…

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Utilizing a Population-Genetic Framework to Test for Gene-Environment Interactions between Zebrafish Behavior and Chemical Exposure (2022) Toxics

Thunga P, Truong L, Rericha Y, Du J, Morshead M, Tanguay RL, Reif DM. Utilizing a Population-Genetic Framework to Test for Gene-Environment Interactions between Zebrafish Behavior and Chemical Exposure. Toxics. 2022 Dec 9;10(12):769. doi: 10.3390/toxics10120769. PMID: 36548602; PMCID: PMC9781692.

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Preethi successfully defends her PhD dissertation!!!

Preethi Thunga successfully defended her PhD dissertation, entitled 'Using zebrafish behavior to study gene-environment interactions after chemical exposures".

 

 

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David joins NIEHS as Chief of the Predictive Toxicology Branch (PTB) in the Division of Translational Toxicology (DTT)

David joined NIH/NIEHS/DTT as Chief of the Predictive Toxicology Branch in October 2022.

The Predictive Toxicology Branch (PTB) partners across the NIEHS Division of Translational Toxicology (DTT) to develop and apply innovative approaches to predict human-relevant health effects from agents of …

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Dylan joins U.S. EPA as a postdoc in the Center for Public Health and Environmental Assessment

Dr. Dylan Wallis is now a postdoc at the U.S. EPA Center for Public Health and Environmental Assessment with Dr. Jeffrey Minucci.

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Retreat and student exchange with Tanguay Lab

Following a joint scientific retreat with Robyn Tanguay's group at Oregon State University (Including a beautiful waterfall hike!), they generously hosted Preethi Thunga at SARL so that she could gain better understanding of data generation for her dissertation work.  

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Adrian joins Sciome as a Senior Computational Toxicologist

Dr. Adrian Green has joined Sciome as a Senior Computational Toxicologist.

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Wildfires and extracellular vesicles: Exosomal MicroRNAs as mediators of cross-tissue cardiopulmonary responses to biomass smoke (2022) Environ Int.

Carberry CK, Koval LE, Payton A, Hartwell H, Ho Kim Y, Smith GJ, Reif DM, Jaspers I, Ian Gilmour M, Rager JE. Wildfires and extracellular vesicles: Exosomal MicroRNAs as mediators of cross-tissue cardiopulmonary responses to biomass smoke. Environ Int. 2022 Jul 16;167:107419. doi: 10.1016/j.envint.2…

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New NIH R01 grant awarded! "Characterizing Gene-Environment Interactions that Affect Individual Susceptibility to an Expanding Chemical Exposome"

Environmental chemical exposure has been linked to increases in cancer incidence, birth and developmental defects, impaired cognitive development, and neurodegenerative disease. However, even as the number of manufactured chemicals in the environment grows into the hundreds-of-thousands, comprehensi…

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Development of the InTelligence And Machine LEarning (TAME) Toolkit for Introductory Data Science, Chemical-Biological Analyses, Predictive Modeling, and Database Mining for Environmental Health Research (2022) Front. Tox

Kyle Roell, Lauren E. Koval, Rebecca Boyles, Grace Patlewicz, Caroline Ring, Cynthia V. Rider, Cavin Ward-Caviness, David M. Reif, Ilona Jaspers, Rebecca C. Fry and Julia E. Rager. Development of the InTelligence And Machine LEarning (TAME) Toolkit for Introductory Data Science, Chemical-Biological …

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Preethi selected for A2i program

Preethi Thunga was selected to take part in the Accelerate to Industry (A2i)™program with the NC State Graduate School. This selective program advances professional development skills, with an emphasis on leadership, teamwork, and communication. For more details, see:

https://grad.ncsu.edu/pro…

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New NIH R35 RIVER grant (PI Robyn Tanguay) awarded!

David is part of a new, 8-year R35 RIVER grant from the National Institute of Environmental Health Sciences (R35ES031709) for the project “Discovering Chemical Activity Networks-Predicting Bioactivity Based on Structure.” The project builds on the long-standing collaboration with Robyn Tanguay at Or…

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David participates in the "From Free Radicals to Key Characteristics" workshop at UC Berkeley

The event brought together experts to celebrate the leadership of Prof. Martyn Smith in developing the "Key Characteristics of Human Carcinogens" and collaborate on future directions for the Key Characteristics approach.

https://www.eventbrite.com/e/from-free-radicals-to-key-characteristics-ticke…

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David participates in NAS workshop on Artificial Intelligence and Open Data Practices in Chemical Hazard Assessment

David served on the planning committee and moderated sessions as part of the National Academy of Sciences (NAS) Workshops to Support EPA's Development of Human Health Assessments: Artificial Intelligence and Open Data Practices in Chemical Hazard Assessment

https://www.nationalacademies.org/event…

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Jessie wins 2nd place for her poster at SETAC Nontarget Analysis for Environmental Risk Assessment!

A Novel Approach to Evaluating Disease Risk Through the Incorporation of Machine Learning and Lipidomic Data

Jessie Chappel, Mary King, Rachel DeHoog, Livia S. Eberlin, David Reif, Erin S. Baker

https://twitter.com/BakerlabNCSU/status/1528756028728385538/photo/2

https://twitter.com/bakerlab…

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Data Science educational toolkit presented at the Superfund DMAC Quarterly Meeting

The inTelligence And Machine lEarning (TAME) Toolkit for Introductory Data Science, Chemical-Biological Analyses, Predictive Modeling, and Database Mining for Environmental Health Research

Kyle R. Roell, Lauren E. Koval, Rebecca Boyles, Grace Patlewicz, Caroline Ring, Cynthia Rider, Cavin Ward-Ca…

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David participates in NAS workshop on Triangulation of Evidence in Environmental Epidemiology

David served on the planning committee as part of the National Academy of Sciences (NAS) Workshops to Support EPA's Development of Human Health Assessments: Triangulation of Evidence in Environmental Epidemiology

https://www.nationalacademies.org/event/05-09-2022/workshops-to-support-epas-deve…

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Nnamdi's work on using Bioinformatics to improve health equity featured in Superfund newsletter

https://tools.niehs.nih.gov/srp/1/eposted/pdfs/srp_e_posted_notes_2022_05_06_508.pdf

Comparison of National Vulnerability Indices Used by the Centers for Disease Control and Prevention for the COVID-19 Response (2022) Public Health Reports

Wolkin A, Collier S, House J, Reif D, Motsinger-Reif A, Duca L, Sharpe D. Comparison of National Vulnerability Indices Used by the Centers for Disease Control and Prevention for the COVID-19 Response. Public Health Rep. 2022 May 5:333549221090262. doi: 10.1177/00333549221090262. Epub ahead of print.…

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20 blog posts