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Blog posts : "gxe"

Synergistic chemotherapy drug response is a genetic trait in lymphoblastoid cell lines (2019) Frontiers in Genetics

Kyle Roell, Tammy Havener, David Reif*, John Jack, Howard McLeod, Tim Wiltshire, Alison Motsinger-Reif*

Front. Genet. | doi: 10.3389/fgene.2019.00829

Synergistic chemotherapy drug response is a genetic trait in lymphoblastoid cell lines

Lymphoblastoid cell lines (LCL) are a high…

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Population-based toxicity screening in human induced pluripotent stem cell-derived cardiomyocytes (2019) Toxicol Appl Pharmacol

Burnett SD, Blanchette AD, Grimm FA, House JS, Reif DM, Wright FA, Chiu WA,
Rusyn I. Population-based toxicity screening in human induced pluripotent stem
cell-derived cardiomyocytes. Toxicol Appl Pharmacol. 2019 Aug 16;381:114711. doi:
10.1016/j.taap.2019.114711. [Epub ahead of print] PubMed P…

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Determination of chemical-disease risk values to prioritize connections between environmental factors, genetic variants, and human diseases (2019) Toxicology and Applied Pharmacology

Kosnik MB, Reif DM. Determination of chemical-disease risk values to
prioritize connections between environmental factors, genetic variants, and human
diseases. Toxicol Appl Pharmacol. 2019 Jul 16:114674. doi:
10.1016/j.taap.2019.114674. [Epub ahead of print] PubMed PMID: 31323264.

Dr. Adrian Green joins the Reif Lab!

Dr. Adrian Green is a Postdoctoral Research Scholar in the Bioinformatics Research Center at NC State University. He received his Ph.D. in Toxicology at NC State University, and his M.S. in Pharmacology and Toxicology at the University of California, Davis. He received his B.S. in Microbiology (mino…

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NIH / NIEHS grant "Gene-Environment Interactions Causing Differential Susceptibility to Chemical Exposure in High-Throughput Screening"

Marissa Kosnik successfully defends her PhD!

Title - Data integration elucidates connections between environmental factors and health outcomes
 
Abstract : It is well understood that environmental factors contribute to the development of human diseases. Multiple types and sources of data are necessary to address the complex relationsh…

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Reif gives invited seminar at Paris symposium

The workshop, "Fish and amphibian embryos as alternative models in toxicology and teratology" was organized by the Helmholtz Centre for Environmental Research and hosted at L'Oréal headquarters in Paris, France. 

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Neonatal mice exposed to a high-fat diet in utero influence the behaviour of their nursing dam (2018) Proc R Sci B

Neonatal mice exposed to a high-fat diet in utero influence the behaviour of their nursing dam.

Baptissart M, Lamb HE, To K, Bradish C, Tehrani J, Reif D, Cowley M.

Proc Biol Sci. 2018 Nov 14;285(1891). pii: 20181237. doi: 10.1098/rspb.2018.1237.

PMID: 30429298

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GxE publication named an NIEHS "Paper of the Month"

Michele's paper "Elucidating gene-by-environment interactions associated with differential susceptibility to chemical exposure" was cited in the NIEHS newsletter as a Paper of the Month!

https://factor.niehs.nih.gov/2018/9/papers/dert/index.htm

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Kyle Roell successfully defends his PhD!

Kyle Roell successfully defended his PhD, entitled "Statistical Methods for Assessing the Genetic Etiology of Synergistic Drug Interactions".

Dr. Kyle Roell is currently a postdoc with Stephanie Engel in the Department of Epidemiology at UNC Chapel Hill.

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Population genetic diversity in zebrafish lines (2018) Mammalian Genome

Balik-Meisner M, Truong L, Scholl EH, Tanguay RL, Reif DM. Population genetic 
diversity in zebrafish lines. Mamm Genome. 2018 Jan 24. doi:
10.1007/s00335-018-9735-x. [Epub ahead of print] PubMed PMID: 29368091.

https://www.ncbi.nlm.nih.gov/pubmed/29368091

 

 

 

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Reif presents at Environmental Mutagenesis & Genomics Society

David presented a seminar at the annual meeting of the Environmental Mutagenesis & Genomics Society (EMGS), entitled: "Gene-Environment Interactions Associated with Differential Susceptibility to Chemical Exposure".

Reif presents at Triangle Statistical Genetics Meeting

David Reif presented an invited talk at the 2016 Triangle Statistical Genetics Meeting. The event was hosted at SAS, Inc. by the Triangle StatGen Organizing Committee.

 

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13 blog posts