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Blog posts : "david reif"

An introduction to terminology and methodology of chemical synergy -perspectives from across disciplines (2017) Frontiers in Pharmacology

April 3, 2017

Incorporating ToxCast and Tox21 datasets to rank biological activity of chemicals at Superfund sites in North Carolina (2017) Environment International

February 1, 2017

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The Proximity Principle

February 1, 2017

Christy Sadler and colleagues have written a new multimedia article about the Bioinformatics "cluster" at NC State University.

https://sciences.ncsu.edu/news/the-proximity-principle

The term "cluster" is shorthand for the cluster hiring program known as the Chancellor's Faculty Excellence Prog…

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A New Statistical Approach to Characterize Chemical-Elicited Behavioral Effects in High-Throughput Studies Using Zebrafish (2017) PLoS One

January 18, 2017

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A data-driven weighting scheme for multivariate phenotypic endpoints recapitulates zebrafish developmental cascades (2016) TAAP

November 21, 2016
Zhang G, Roell KR, Truong L, Tanguay RL, Reif DM. A data-driven weighting
scheme for multivariate phenotypic endpoints recapitulates zebrafish
developmental cascades. Toxicol Appl Pharmacol. 2016 Nov 21. pii:
S0041-008X(16)30365-9. doi: 10.1016/j.taap.2016.11.010. [Epub ahead of print]
PubMed …

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Embryonic exposure to TCDD impacts osteogenesis of the axial skeleton in Japanese medaka, Oryzias latipes (2016) Toxicological Sciences

November 15, 2016

Embryonic exposure to TCDD impacts osteogenesis of the axial skeleton in Japanese medaka, Oryzias latipes. ALTD Watson, A Planchart, CJ Mattingly, C Winkler, DM Reif, SW Kullman. Toxicological Sciences, kfw229

http://toxsci.oxfordjournals.org/content/early/2016/11/14/toxsci.kfw229.full.pdf+html

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Eigenvector metabolite analysis reveals dietary effects on the association among metabolite correlation patterns, gene expression, and phenotypes (2016) Metabolomics

November 1, 2016

Eigenvector metabolite analysis reveals dietary effects on the association among metabolite correlation patterns, gene expression, and phenotypes. CHS Chialvo, R Che, D Reif, A Motsinger-Reif, LK Reed. Metabolomics 12 (11), 167.

http://link.springer.com/article/10.1007/s11306-016-1117-3

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Analysis of the Effects of Cell Stress and Cytotoxicity on In Vitro Assay Activity Across a Diverse Chemical and Assay Space (2016) Toxicological Sciences

May 20, 2016
Judson R, Houck K, Martin M, Richard AM, Knudsen TB, Shah I, Little S,
Wambaugh J, Woodrow Setzer R, Kothya P, Phuong J, Filer D, Smith D, Reif D,
Rotroff D, Kleinstreuer N, Sipes N, Xia M, Huang R, Crofton K, Thomas RS.
Analysis of the Effects of Cell Stress and Cytotoxicity on In Vitro Assay
…

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Reif co-authors National Academy of Sciences (NAS) report "Application of Modern Toxicology Approaches for Predicting Acute Toxicity for Chemical Defense"

August 24, 2015

David Reif served as a member of an expert committee that authored the report "Application of Modern Toxicology Approaches for Predicting Acute Toxicity for Chemical Defense". 

The official citation is:

National Academies of Sciences, Engineering, and Medicine. Application of Modern Toxicolo…

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Reif part of multi-institute research team awarded EPA grant

August 17, 2015

The Environmental Protection Agency (EPA) has awarded a $6 million grant to fund a multi-institutional collaboration between the Texas A&M College of Veterinary Medicine & Biomedical Sciences and the Bioinformatics Research Center at NCSU. 

More information is available from the BRC and from Tex…

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Impact of Low Dose Oral Exposure to Bisphenol A (BPA) on Juvenile and Adult Rat Exploratory and Anxiety Behavior: A CLARITY-BPA Consortium Study (2015) Toxicological Sciences

July 23, 2015

Rebuli, Camacho, Adonay, Reif, Aylor, Patisaul. Impact of Low Dose Oral Exposure to Bisphenol A (BPA) on Juvenile and Adult Rat Exploratory and Anxiety Behavior: A CLARITY-BPA Consortium Study. (2015) Toxicological Sciences.

http://www.ncbi.nlm.nih.gov/pubmed/26209558

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Reif named Managing Editor of journal BioData Mining

July 13, 2015

David Reif has been named the new Managing Editor of the journal BioData Mining 

BioData Mining is an open-access, peer-reviewed, online journal encompassing research on all aspects of data mining applied to high-dimensional biological and biomedical data, focusing on computational aspects o…

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Toxicity testing in the 21st century beyond environmental chemicals (2015) Altex

July 10, 2015

Costanza Rovida, Shoji Asakura, Mardas Daneshian, Hana Hofman-Huether, Marcel Leist, Leo Meunier, David Reif, Anna Rossi, Markus Schmutz, Jean-Pierre Valentin, Joanne Zurlo, Thomas Hartung.Toxicity testing in the 21st century beyond environmental chemicals. (2015) Altex 32 (3), 171-181.

http://w…

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High-throughput characterization of chemical-associated embryonic behavioral changes predicts teratogenic outcomes (2015) Archives of Toxicology

July 1, 2015

High-throughput characterization of chemical-associated embryonic behavioral changes predicts teratogenic outcomes (2015) Archives of Toxicology

http://www.ncbi.nlm.nih.gov/pubmed/26126630

(NOTE: Full-text available for free via link above or here)

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Reif serves on expert Working Group for the World Health Organization's (WHO) International Agency for Cancer Research (IARC)

June 23, 2015

David Reif was a member of the Working Group that drew experts from 13 countries to a meeting in Lyon, France in order to evaluate the carcinogenicity of the the insecticides gamma-hexachlorocyclohexane (lindane) and dichlorodiphenyltrichloroethane (DDT) and the herbicide 2,4-dichlorophenoxyacetic a…

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Molecular cloning, functional characterization, and evolutionary analysis of vitamin d receptors isolated from Basal vertebrates (2015) PLoS One

April 9, 2015

http://www.ncbi.nlm.nih.gov/pubmed/25855982

16 blog posts