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Blog posts : "interdisciplinary"

Confirmation of high-throughput screening data and novel mechanistic insights into VDR-xenobiotic interactions by orthogonal assays (2018) Scientific Reports

Mahapatra D, Franzosa JA, Roell K, Kuenemann MA, Houck KA, Reif DM, Fourches
D, Kullman SW. Confirmation of high-throughput screening data and novel
mechanistic insights into VDR-xenobiotic interactions by orthogonal assays. Sci
Rep. 2018 Jun 11;8(1):8883. doi: 10.1038/s41598-018-27055-3. PubMe…

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ToxPi Graphical User Interface 2.0: Dynamic exploration, visualization, and sharing of integrated data models (2018) BMC Bioinformatics

Marvel SW, To K, Grimm FA, Wright FA, Rusyn I, Reif DM. ToxPi Graphical User Interface 2.0: Dynamic exploration, visualization, and sharing of integrated data models. BMC Bioinformatics. 2018 Mar 5;19(1):80. doi: 10.1186/s12859-018-2089-2. PubMed PMID: 29506467.

 

https://bmcbioinformatics.bi…

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National Academies meeting: "Informing Environmental Health Decisions Through Data Integration"

David Reif was a moderator and member of the planning committee for the National Academy of Sciences workshop "Informing Environmental Health Decisions Through Data Integration". 

The workshop brought together thought leaders from diverse fields to explore the promise and potential pitfalls of e…

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Use of high-throughput in vitro toxicity screening data in cancer hazard evaluations by IARC Monograph Working Groups (2017) ALTEX

Reif presents at OpenTox conference

David Reif presented at the 2017 OpenTox USA meeting. Thanks to Barry Hardy and Noffisat Oki for the invitation to speak! 

His seminar was entitled "Implications of Population Genetic Diversity for Safety Assessment."  

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Reif presents at International Neurotoxicology Association meeting in Brazil

David Reif presented at the joint meeting of the International Neurotoxicology Association & Neurotoxicity Society in Florianopolis, Brazil. 

The seminar was entitled "Developing an Integrated Testing Strategy: Analytical methods to distill useful information from high-throughput screening of ch…

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The Proximity Principle

Christy Sadler and colleagues have written a new multimedia article about the Bioinformatics "cluster" at NC State University.

https://sciences.ncsu.edu/news/the-proximity-principle

The term "cluster" is shorthand for the cluster hiring program known as the Chancellor's Faculty Excellence Prog…

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Eigenvector metabolite analysis reveals dietary effects on the association among metabolite correlation patterns, gene expression, and phenotypes (2016) Metabolomics

Eigenvector metabolite analysis reveals dietary effects on the association among metabolite correlation patterns, gene expression, and phenotypes. CHS Chialvo, R Che, D Reif, A Motsinger-Reif, LK Reed. Metabolomics 12 (11), 167.

http://link.springer.com/article/10.1007/s11306-016-1117-3

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Marissa Kosnik joins the Reif Lab!

Bio

Marissa is pursuing her PhD in the Toxicology graduate program.

University Global Partnership Network (UGPN) award!

Jane Hoppin and David Reif received a University Global Partnership Network Collaboration Fund grant to work with researchers at the University of Wollongong in Australia. The proposal was entitled ‘An international alliance for Population, Wellbeing and Environment Research’.  

Drs. T…

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Aggregate entropy scoring for quantifying activity across endpoints with irregular correlation structure (2016) Reproductive Toxicology

Zhang G, Marvel S, Truong L, Tanguay RL, Reif DM. Aggregate entropy scoring
for quantifying activity across endpoints with irregular correlation structure.
Reprod Toxicol. 2016 Apr 27;62:92-99. doi: 10.1016/j.reprotox.2016.04.012. [Epub 
ahead of print] PubMed PMID: 27132190.

Selected as cov…

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Reif named Associate Editor at Environmental Health Perspectives

David Reif has been named to the Board of Associate Editors of the journal Environmental Health Perspectives 

 

The mission of Environmental Health Perspectives (EHP) is to serve as a forum for the discussion of the interrelationships between the environment and human health by publishing…

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Reif co-authors National Academy of Sciences (NAS) report "Application of Modern Toxicology Approaches for Predicting Acute Toxicity for Chemical Defense"

David Reif served as a member of an expert committee that authored the report "Application of Modern Toxicology Approaches for Predicting Acute Toxicity for Chemical Defense". 

The official citation is:

National Academies of Sciences, Engineering, and Medicine. Application of Modern Toxicolo…

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Reif part of multi-institute research team awarded EPA grant

The Environmental Protection Agency (EPA) has awarded a $6 million grant to fund a multi-institutional collaboration between the Texas A&M College of Veterinary Medicine & Biomedical Sciences and the Bioinformatics Research Center at NCSU. 

More information is available from the BRC and from Tex…

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Impact of Low Dose Oral Exposure to Bisphenol A (BPA) on Juvenile and Adult Rat Exploratory and Anxiety Behavior: A CLARITY-BPA Consortium Study (2015) Toxicological Sciences

Rebuli, Camacho, Adonay, Reif, Aylor, Patisaul. Impact of Low Dose Oral Exposure to Bisphenol A (BPA) on Juvenile and Adult Rat Exploratory and Anxiety Behavior: A CLARITY-BPA Consortium Study. (2015) Toxicological Sciences.

http://www.ncbi.nlm.nih.gov/pubmed/26209558

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Reif named Managing Editor of journal BioData Mining

David Reif has been named the new Managing Editor of the journal BioData Mining 

BioData Mining is an open-access, peer-reviewed, online journal encompassing research on all aspects of data mining applied to high-dimensional biological and biomedical data, focusing on computational aspects o…

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Toxicity testing in the 21st century beyond environmental chemicals (2015) Altex

Costanza Rovida, Shoji Asakura, Mardas Daneshian, Hana Hofman-Huether, Marcel Leist, Leo Meunier, David Reif, Anna Rossi, Markus Schmutz, Jean-Pierre Valentin, Joanne Zurlo, Thomas Hartung.Toxicity testing in the 21st century beyond environmental chemicals. (2015) Altex 32 (3), 171-181.

http://w…

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High-throughput characterization of chemical-associated embryonic behavioral changes predicts teratogenic outcomes (2015) Archives of Toxicology

High-throughput characterization of chemical-associated embryonic behavioral changes predicts teratogenic outcomes (2015) Archives of Toxicology

http://www.ncbi.nlm.nih.gov/pubmed/26126630

(NOTE: Full-text available for free via link above or here)

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Center for Human Health and the Environment awarded major NIEHS grant!

The Center for Human Health and the Environment (CHHE) was awarded a NIH/NIEHS P30 grant. This multidisciplinary center involves researchers from across NC State University and East Carolina University. David Reif leads the Bioinformatics Team, which works to develop novel computational tools and a…

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Galen Collier brings his research to NC State!

Dr. Galen Collier has joined the NC State Bioinformatics community. As a Research Scholar within the transdisciplinary Department of Biological Sciences, he is working on collaborative projects with Carolyn Mattingly, Fred Wright, and David Reif.  

Bio

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20 blog posts