Kimberly T. To, Rebecca C. Fry, David M. Reif. Characterizing the effects of missing data and evaluating imputation methods for chemical prioritization applications using ToxPi. BioData Mining. 2018.
https://rdcu.be/XYtJ
Blog posts : "Publications"
Confirmation of high-throughput screening data and novel mechanistic insights into VDR-xenobiotic interactions by orthogonal assays (2018) Scientific Reports
Mahapatra D, Franzosa JA, Roell K, Kuenemann MA, Houck KA, Reif DM, Fourches
D, Kullman SW. Confirmation of high-throughput screening data and novel
mechanistic insights into VDR-xenobiotic interactions by orthogonal assays. Sci
Rep. 2018 Jun 11;8(1):8883. doi: 10.1038/s41598-018-27055-3. PubMe…
ToxPi Graphical User Interface 2.0: Dynamic exploration, visualization, and sharing of integrated data models (2018) BMC Bioinformatics
Marvel SW, To K, Grimm FA, Wright FA, Rusyn I, Reif DM. ToxPi Graphical User Interface 2.0: Dynamic exploration, visualization, and sharing of integrated data models. BMC Bioinformatics. 2018 Mar 5;19(1):80. doi: 10.1186/s12859-018-2089-2. PubMed PMID: 29506467.
Population genetic diversity in zebrafish lines (2018) Mammalian Genome
Balik-Meisner M, Truong L, Scholl EH, Tanguay RL, Reif DM. Population genetic diversity in zebrafish lines. Mamm Genome. 2018 Jan 24. doi: 10.1007/s00335-018-9735-x. [Epub ahead of print] PubMed PMID: 29368091.
https://www.ncbi.nlm.nih.gov/pubmed/29368091
Use of high-throughput in vitro toxicity screening data in cancer hazard evaluations by IARC Monograph Working Groups (2017) ALTEX
WA Chiu, KZ Guyton, MT Martin, DM Reif, I Rusyn. ALTEX. 2017.
Transgenerational inheritance of neurobehavioral and physiological deficits from developmental exposure to benzo [a] pyrene in zebrafish (2017) Toxicology and Applied Pharmacology
Knecht AL, Truong L, Marvel SW, Reif DM, Garcia A, Lu C, Simonich MT, Teeguarden JG, Tanguay RL. Transgenerational inheritance of neurobehavioral and physiological deficits from developmental exposure to benzo[a]pyrene in zebrafish. Toxicol Appl Pharmacol. 2017 Jun 3;329:148-157. doi: 10.1016/…
An introduction to terminology and methodology of chemical synergy -perspectives from across disciplines (2017) Frontiers in Pharmacology
K Roell, D Reif, A Motsinger-Reif (2017) An introduction to terminology and methodology of chemical synergy-perspectives from across disciplines. Frontiers in Pharmacology.
Integrating Morphological and Behavioral Phenotypes in Developing Zebrafish
Zhang G., Truong L., Tanguay R.L., Reif D.M. (2017) Integrating Morphological and Behavioral Phenotypes in Developing Zebrafish. In: Kalueff A. (eds) The rights and wrongs of zebrafish: Behavioral phenotyping of zebrafish. Springer, Cham.
http://www.springer.com/us/book/9783319337739
https://l…
A data-driven weighting scheme for multivariate phenotypic endpoints recapitulates zebrafish developmental cascades (2016) TAAP
Zhang G, Roell KR, Truong L, Tanguay RL, Reif DM. A data-driven weighting
scheme for multivariate phenotypic endpoints recapitulates zebrafish
developmental cascades. Toxicol Appl Pharmacol. 2016 Nov 21. pii:
S0041-008X(16)30365-9. doi: 10.1016/j.taap.2016.11.010. [Epub ahead of print]
PubMed …
Embryonic exposure to TCDD impacts osteogenesis of the axial skeleton in Japanese medaka, Oryzias latipes (2016) Toxicological Sciences
Embryonic exposure to TCDD impacts osteogenesis of the axial skeleton in Japanese medaka, Oryzias latipes. ALTD Watson, A Planchart, CJ Mattingly, C Winkler, DM Reif, SW Kullman. Toxicological Sciences, kfw229
http://toxsci.oxfordjournals.org/content/early/2016/11/14/toxsci.kfw229.full.pdf+html
Eigenvector metabolite analysis reveals dietary effects on the association among metabolite correlation patterns, gene expression, and phenotypes (2016) Metabolomics
Eigenvector metabolite analysis reveals dietary effects on the association among metabolite correlation patterns, gene expression, and phenotypes. CHS Chialvo, R Che, D Reif, A Motsinger-Reif, LK Reed. Metabolomics 12 (11), 167.
http://link.springer.com/article/10.1007/s11306-016-1117-3
Article featured as Editor's Highlight in Toxicological Sciences
Judson R, Houck K, Martin M, Richard AM, Knudsen TB, Shah I, Little S, Wambaugh J, Woodrow Setzer R, Kothya P, Phuong J, Filer D, Smith D, Reif D, Rotroff D, Kleinstreuer N, Sipes N, Xia M, Huang R, Crofton K, Thomas RS. Editor's Highlight: Analysis of the Effects of Cell Stress and Cytotoxicit…
Advancing toxicology research using in vivo high throughput toxicology with small fish models (2016) ALTEX
Planchart A, Mattingly CJ, Allen D, Ceger P, Casey W, Hinton D, Kanungo J,
Kullman SW, Tal T, Bondesson M, Burgess SM, Sullivan C, Kim C, Behl M, Padilla S,
Reif DM, Tanguay RL, Hamm J. Advancing toxicology research using in vivo high
throughput toxicology with small fish models. ALTEX. 2016 Ju…
Analysis of the Effects of Cell Stress and Cytotoxicity on In Vitro Assay Activity Across a Diverse Chemical and Assay Space (2016) Toxicological Sciences
Judson R, Houck K, Martin M, Richard AM, Knudsen TB, Shah I, Little S,
Wambaugh J, Woodrow Setzer R, Kothya P, Phuong J, Filer D, Smith D, Reif D,
Rotroff D, Kleinstreuer N, Sipes N, Xia M, Huang R, Crofton K, Thomas RS.
Analysis of the Effects of Cell Stress and Cytotoxicity on In Vitro Assay
…
A chemical-biological similarity-based grouping of complex substances as a prototype approach for evaluating chemical alternatives (2016) Green Chemistry
F. A. Grimm, Y. Iwata, O. Sirenko, G. A. Chappell, F. A. Wright, D. M. Reif, J. Braisted, D. L. Gerhold, J. M. Yeakley, P. Shepard, B. Seligmann, T. Roy, P. J. Boogaard, H. B. Ketelslegers, A. M. Rohde and I. Rusyn, Green Chem., 2016, DOI: 10.1039/C6GC01147K.
Open Access / Freely-available:
ht…
Advancing Exposure Science through Chemical Data Curation and Integration in the Comparative Toxicogenomics Database (2016) Environmental Health Perspectives
Grondin CJ, Davis AP, Wiegers TC, King BL, Wiegers JA, Reif DM, Hoppin JA,
Mattingly CJ. Advancing Exposure Science through Chemical Data Curation and
Integration in the Comparative Toxicogenomics Database. Environ Health Perspect.
2016 May 12. [Epub ahead of print] PubMed PMID: 27170236.
Aggregate entropy scoring for quantifying activity across endpoints with irregular correlation structure (2016) Reproductive Toxicology
Zhang G, Marvel S, Truong L, Tanguay RL, Reif DM. Aggregate entropy scoring
for quantifying activity across endpoints with irregular correlation structure.
Reprod Toxicol. 2016 Apr 27;62:92-99. doi: 10.1016/j.reprotox.2016.04.012. [Epub
ahead of print] PubMed PMID: 27132190.
Selected as cov…